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Dual GIP and GLP-1 receptor agonist tirzepatide improves Beta-cell function and insulin sensitivity in type 2 diabetes

It works by enhancing insulin production and reducing the glucagon secretion in a glucose-dependent manner, which helps lower blood sugar levels

Exciting times, but careful evaluation of long-term safety, real-world outcomes, and patient access will be key From a neurological perspective, this overview is helpful, but what may become even more important is understanding how hormonal status shapes metabolic response

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Additional information Peer review information Nature Microbiology thanks Marc Donath, Lesley Hoyles and Liping Zhao for their contribution to the peer review of this work